Cardinals QB Kyler Murray said he had severe DIARRHEA early Sunday at 4:30 am before the game vs. Saints💩 “I woke up at 4:30. I was like, I knew some sh*t wasn’t right. Immediately to the toilet…I had to take some Imodium to keep the f*cking, to keep my stomach from f*cking with me,” Murray said. “It was all good, though. We got the W.

Kyler Murray, quarterback for the Arizona Cardinals, recently made headlines not just for his performance on the field, but for a rather candid and unexpected revelation about what he went through before taking the field against the New Orleans Saints. In a post-game interview that was both raw and refreshingly unfiltered, Murray shared details of a rough early morning episode that might have derailed his game day — but didn’t. According to Murray, he woke up at 4:30 in the morning with severe diarrhea, a moment he described with absolute certainty as something being seriously wrong. “I woke up at 4:30. I was like, I knew some sh*t wasn’t right,” he said, speaking frankly about the discomfort and panic that hit him in the early hours before kickoff.

From there, things escalated quickly. “Immediately to the toilet,” Murray continued, painting a vivid picture of the unpleasant start to his day. While many athletes might have chosen to downplay or outright ignore something so personal, Murray opted to be straightforward, maybe even brutally honest. He explained that in order to manage the situation and avoid further complications that might affect his ability to play, he turned to Imodium, a common over-the-counter anti-diarrheal medication. “I had to take some Imodium to keep the fcking, to keep my stomach from fcking with me,” Murray said, showing both the urgency of the situation and the real human side of what it takes to perform at an elite level even when your body is working against you.

This level of transparency is unusual in professional sports, where athletes are often expected to project toughness, resilience, and unshakable focus at all times. Murray’s openness not only breaks down that barrier but also reminds fans and observers that professional athletes are human beings dealing with the same unpredictable and inconvenient bodily functions as anyone else. It takes a certain kind of confidence and self-assurance to admit to something like that publicly — especially when the public can be unforgiving or quick to turn even the most minor slip-ups into memes or punchlines. But Murray wasn’t ashamed. In fact, he ended his account with a shrug and a smile, as if to say, “Yeah, it happened. And I still showed up.”

He didn’t let the rough start dictate the rest of the day. “It was all good, though. We got the W,” he concluded, placing the focus back on what mattered most to him — the win. And that’s a key part of this story. Despite whatever was happening with his digestive system in the hours leading up to the game, Kyler Murray went out there and performed. He did his job. He didn’t let a miserable morning define the afternoon. For someone dealing with the kind of intense physical and mental demands that come with being an NFL quarterback, especially one in the spotlight like Murray, it’s impressive to maintain composure, execute the game plan, and lead the team to a victory under such uncomfortable circumstances.

It also adds another dimension to the conversation about what athletes endure behind the scenes. Fans usually see the polished product — the throws, the runs, the touchdowns, the celebrations. But what they don’t always see is the effort it takes just to get on the field. Whether it’s injuries, fatigue, illness, or in this case, something as unglamorous as diarrhea at dawn, the road to game time is often paved with discomfort and adversity. And yet, expectations remain sky-high. Quarterbacks especially are expected to be leaders, to have poise under pressure, and to make high-stakes decisions in real time — all while cameras are rolling and the outcome of the game rests on their shoulders. Knowing that Murray was battling a very real and unpleasant issue in the hours before kickoff only underscores the kind of mental focus and discipline required to compartmentalize and compete.

In some ways, Murray’s honesty could even be seen as a strength, not a liability. It’s easy to talk about resilience in the abstract, to celebrate grit and perseverance when it comes in neatly packaged narratives. But here, we have an example of that resilience in a much messier, more relatable form. He didn’t romanticize it. He didn’t spin it into a motivational cliché. He just told the truth. He was sick, he dealt with it, and he went to work. There’s something admirable about that — the lack of pretense, the refusal to act like everything is always under control. It’s a reminder that toughness doesn’t always look like gritted teeth and heroic speeches. Sometimes, it looks like a guy chugging water, popping Imodium, and dragging himself through a brutal morning because there’s a job to do.

Reactions from fans and media were a mix of amusement, admiration, and surprise. Some found it hilarious, others found it gutsy, and a few probably wondered whether too much information had been shared. But in an era when authenticity is rare and often manufactured for effect, Murray’s blunt and humorous take on a deeply human experience stood out. It made him more relatable, more three-dimensional. It also sparked plenty of conversations online, as fans debated whether they could have performed at that level in the same situation. Spoiler: most couldn’t.

There’s also a layer of camaraderie in stories like this. Ask any athlete who’s been playing long enough, and they’ll likely have a tale about a game they played while sick, injured, or otherwise less than 100%. It’s part of the grind. You learn to manage your body, your mind, your nerves — and sometimes, your stomach — in order to perform when it matters. For Murray, this was just one more challenge in a career that’s already seen its share of highs and lows. It won’t define his legacy, but it adds texture to it. It’s a reminder that behind every highlight reel throw or clutch run, there’s a person managing things you’ll never see on the stat sheet.

In the end, the Cardinals got the win, and Murray did what he had to do. The box score won’t reflect what he went through before kickoff, but his story might stick in fans’ minds longer than some of his throws. Because it’s not just about what happens on the field — it’s about everything it takes to get there. And sometimes, that includes overcoming a 4:30 a.m. wake-up call from your own gut.

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